عنوان المقالة:المايكرويف ساعدت في التخليق والفعالية البايولوجية لمركبات الاستر والهيدرازايد من دواء السبروفلوكسلسين Microwave-assisted synthesis and biological activity of ester, carbothioate and carbohydrazide derivative compounds of the drug Ciprofloxacin
ا.م.د. نادية صادق مجيد | Assist.Prof.Dr. Nadia Sadiq Majeed | 5269
نوع النشر
مجلة علمية
المؤلفون بالعربي
نادية صادق مجيد , ناظر نجم عبد الله
المؤلفون بالإنجليزي
Nadia Sadiq Majeed, Nadhir N. A.Jafar
الملخص العربي
Our work aimed to organic synthesis and biological investigation of newly ciprofloxacin derivative as ester, thioester and hydrazine form by using microwave irradiation. The synthesis compounds were identified and confirmed by IR, 1HNMR, 13CNMR and elemental analysis. All these derivatives were tested against different bacteria. The result found that all compounds have better biological activity comparable with Ciprofloxacin itself.
الملخص الانجليزي
Our work aimed to organic synthesis and biological investigation of newly ciprofloxacin derivative as ester, thioester and hydrazine form by using microwave irradiation. The synthesis compounds were identified and confirmed by IR, 1HNMR, 13CNMR and elemental analysis. All these derivatives were tested against different bacteria. The result found that all compounds have better biological activity comparable with Ciprofloxacin itself.
تاريخ النشر
05/03/2017
الناشر
Journal of Chemical and Pharmaceutical Sciences
رقم المجلد
1
رقم العدد
ISSN/ISBN
0974-2115
رابط الملف
تحميل (147 مرات التحميل)
الكلمات المفتاحية
Ciprofloxacin, Ester, Carbothioate, Carbohydrazide, Fluroquinolone.
رجوع