عنوان المقالة: Comparison of CD19, CD8 and FOXP3 Expression among Hydatid Human Liver Infection
سوسن محمد جبار الحسناوي | Sawsan M. Jabbar AL-Hasnawi | 3128
- نوع النشر
- مجلة علمية
- المؤلفون بالعربي
- المؤلفون بالإنجليزي
- 1Atyaf ali Kadim Al-asadi, 2Dhamiaa M. Hamza, 3 Sawsan M.Jabbar Al-Hasnawi
- الملخص الانجليزي
- Background: Cystic echinococcosis is a parasitic zoonosis that causes significant economic losses and poses a threat to public health, is caused by larvae of the tapeworm Echinococcus granulosus the aim of this study was to quantification of protein expiration of CD markers (cd8, cd19, foxp3) with hepatic infection with hydatid cyst in human by image j technique and compare immune response between each other for these biomarker use immunohistochemistry technique (IHC). METHOD: One- hundred blocks collected from Al Hussein Teaching Hospital and Noor alhussain medical laboratory .Control group blocks were collected from unit of forensic medicine at Al-Hussein Teaching Hospital, in Th-Qar, Iraq. RESULT: (IHC)where performed on CD markers(cd8,cd19,foxp3), the result was show CD19 monoclonal antibody expression was the predominant marker increase compared to other marker ,The CD8and FOXP3corresponds to T-Cell and T-Reg, that the mean expression of CD8 comes after CD19expression and followed byFOXP3.Although the immune expiration of Foxp3 in the disease group show the most lower expiration For conclusion different immune cell showed to be involved in local response to humane hydatid cyst. in addition for the significant higher of expression of CD19 which suggest important role of B-cell in that site.
- تاريخ النشر
- 05/06/2020
- الناشر
- International Journal of Medical Science and Current Research (IJMSCR)
- رقم المجلد
- 3
- رقم العدد
- 3
- ISSN/ISBN
- 2209-2862
- الصفحات
- 156-162
- رابط الملف
- تحميل (50 مرات التحميل)
- الكلمات المفتاحية
- NIL