1Atyaf ali Kadim Al-asadi, 2Dhamiaa M. Hamza, 3 Sawsan M.Jabbar Al-Hasnawi
الملخص الانجليزي
Background: Cystic echinococcosis is a parasitic zoonosis that causes significant economic losses and poses a
threat to public health, is caused by larvae of the tapeworm Echinococcus granulosus the aim of this study was
to quantification of protein expiration of CD markers (cd8, cd19, foxp3) with hepatic infection with hydatid cyst
in human by image j technique and compare immune response between each other for these biomarker use
immunohistochemistry technique (IHC). METHOD: One- hundred blocks collected from Al Hussein Teaching
Hospital and Noor alhussain medical laboratory .Control group blocks were collected from unit of forensic
medicine at Al-Hussein Teaching Hospital, in Th-Qar, Iraq. RESULT: (IHC)where performed on CD
markers(cd8,cd19,foxp3), the result was show CD19 monoclonal antibody expression was the predominant
marker increase compared to other marker ,The CD8and FOXP3corresponds to T-Cell and T-Reg, that the
mean expression of CD8 comes after CD19expression and followed byFOXP3.Although the immune expiration
of Foxp3 in the disease group show the most lower expiration For conclusion different immune cell showed to
be involved in local response to humane hydatid cyst. in addition for the significant higher of expression of
CD19 which suggest important role of B-cell in that site.
تاريخ النشر
05/06/2020
الناشر
International Journal of Medical Science and Current Research (IJMSCR)
سوسن محمد جبار الحسناوي | Sawsan M. Jabbar AL-Hasnawi | 3045