عنوان المقالة:المايكرويف ساعدت في التخليق والفعالية البايولوجية لمركبات الاستر والهيدرازايد من دواء السبروفلوكسلسين Microwave-assisted synthesis and biological activity of ester, carbothioate and carbohydrazide derivative compounds of the drug Ciprofloxacin
Our work aimed to organic synthesis and biological investigation of newly ciprofloxacin derivative as ester,
thioester and hydrazine form by using microwave irradiation. The synthesis compounds were identified and
confirmed by IR, 1HNMR, 13CNMR and elemental analysis. All these derivatives were tested against different
bacteria. The result found that all compounds have better biological activity comparable with Ciprofloxacin itself.
Abstract
Our work aimed to organic synthesis and biological investigation of newly ciprofloxacin derivative as ester,
thioester and hydrazine form by using microwave irradiation. The synthesis compounds were identified and
confirmed by IR, 1HNMR, 13CNMR and elemental analysis. All these derivatives were tested against different
bacteria. The result found that all compounds have better biological activity comparable with Ciprofloxacin itself.
نادية صادق مجيد | Nadia Sadiq Majeed | 4714